Amal Alhefdhi

• Name: Amal Y. Alhefdhi, MD, PhD, MSc
• Specialty: Breast & Endocrine Surgery / General Surgery
• Current institution: King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
• Academic position: Associate Professor, Alfaisal University
• Clinical areas: Breast surgery, breast cancer, endocrine surgery, thyroid surgery, thyroid cancer and parathyroid disease.

Education & Training

Available professional records indicate advanced training in breast and endocrine surgery, clinical investigation and medical higher-education leadership at the University of Wisconsin–Madison. Her professional credentials are listed as MBBS, SB-Surg, ABIS, MS and EdD in her research profile.

Clinical & Research Expertise

Dr. Alhefdhi's research and clinical interests include:

• Breast cancer diagnosis and surgical management
• Breast and endocrine surgery
• Thyroid cancer and thyroid nodules
• Parathyroid disease and hyperparathyroidism
• Breast cancer in young women
• Male breast cancer
• Breast cancer metastasis and surgical treatment
• Surgical outcomes and cancer care
• Endocrine surgery during and after the COVID-19 pandemic.

Research & Achievements

Dr. Alhefdhi has been a principal investigator and co-principal investigator on several KFSH&RC research projects. These have included research into breast cancer characteristics in women aged 40 or younger, thyroid cancer prediction using preoperative biomarkers, breast cancer treatment delays, endocrine surgery outcomes and breast cancer with isolated liver metastasis.

She has also contributed to peer-reviewed research, including the 2022 study “Factors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer,” which examined predictors of positive sentinel lymph nodes in breast cancer patients.

Another publication, from 2023, examined the unusual coexistence of Multiple Endocrine Neoplasia Type 1 (MEN1) and breast cancer in a young Saudi woman, demonstrating her research interest at the intersection of endocrine disease and breast oncology.

Her earlier work has also included research on primary hyperparathyroidism, endocrine surgery and breast cancer, including collaboration with researchers at the University of Wisconsin.

Selected Research Leadership

KFSH&RC records identify Dr. Alhefdhi as principal investigator for projects including:

1. Characteristics of Breast Cancer in Patients 40 Years of Age or Younger — investigating breast cancer characteristics in young Saudi women.
2. Can Preoperative Serum Thyroglobulin and Anti-Thyroglobulin Levels Predict Thyroid Cancer? — investigating potential predictors of malignancy in thyroid nodules.
3. Outcomes of Breast Cancer Patients with Isolated Liver Metastasis — comparing surgical resection with other local treatment modalities.
4. Surgical Outcome of Parathyroidectomy for Tertiary Hyperparathyroidism Post Renal Transplantation in Saudi Arabia.
5. Research into diagnostic and treatment delays during the COVID-19 pandemic in endocrine surgery patients.